Risk factors and predictive effectiveness of PI-RADS after targeted combined system puncture for CsPCa patients with 3 points
10.3969/j.issn.1009-8291.2023.08.011
- VernacularTitle:行靶向联合系统穿刺PI-RADS评分3分患者确诊具有临床意义前列腺癌的危险因素及其预测效能
- Author:
Weiqiang HU
1
;
Weimin GAN
1
;
Xiaoqun YAO
2
;
Jianguang HE
1
;
Ning DING
1
;
Kunlong LIU
1
;
Liuyong ZHANG
1
;
Junping WANG
2
;
Hui LIU
2
Author Information
1. Department of Urology, Xi’an Gaoxin Hospital, Xi’an 710077, China
2. Department of Radiology, Xi’an Gaoxin Hospital, Xi’an 710077, China
- Publication Type:Journal Article
- Keywords:
puncture;
prostate imaging reporting and data system;
magnetic resonance;
clinically significant prostate cancer
- From:
Journal of Modern Urology
2023;28(8):692-695
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the risk factors and predictive effectiveness of prostate imaging reporting and data system (PI-RADS) score for patients with clinically significant prostate cancer (CsPCa) whose PI-RADS score was 3, so as to provide evidence for the diagnosis and treatment. 【Methods】 The clinical and multi-parameter magnetic resonance imaging (mpMRI) data of 153 CsPCa patients treated during Jan.2017 and Dec.2021 whose PI-RADS score was 3 were retrospectively analyzed. With PI-RADS score of 3 as the independent risk factor for CsPCa, the other relevant independent risk factors in predicting CsPCa were evaluated. 【Results】 Univariate and multivariate analyses showed that prostate-specific antigen (PSA) density and apparent dispersion coefficient (ADC) were independent risk factors for the diagnosis of CsPCa (P<0.05). Analysis of receiver operating characteristic (ROC) curve showed that combined PSA density and ADC were more effective than PSA density and ADC alone (P<0.05). 【Conclusion】 The combination of PSA density and ADC can guide clinicians to identify high-risk CsPCa patients from patients with PI-RADS score of 3 points.
