Efficacy of ThULEP versus HoLEP in treating benign prostatic hyperplasia: a Meta analysis
10.3969/j.issn.1009-8291.2023.09.007
- VernacularTitle:ThULEP与HoLEP治疗良性前列腺增生疗效比较的Meta分析
- Author:
Yinghao ZHOU
1
;
Wandong YU
1
;
Hangbin MA
1
;
Xuehu ZHANG
1
;
Cheng ZHOU
1
;
Guowei SHI
1
Author Information
1. Department of Urology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai 200240, China
- Publication Type:Journal Article
- Keywords:
thulium laser enucleation of the prostate;
holmium laser enucleation of the prostate;
benign prostatic hyperplasia;
Meta analysis;
systematic review
- From:
Journal of Modern Urology
2023;28(9):764-769
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To compare the efficacy and safety of thulium laser enucleation of the prostate (ThULEP) and holmium laser enucleation of the prostate (HoLEP) in the treatment of benign prostatic hyperplasia (BPH). 【Methods】 Randomized controlled trials (RCTs) and clinical controlled trials (CCTs) were searched in PubMed, Embase, Cochrane Library, CNKI and Wanfang Database from Jan.1,2010 to May 30,2022. Two reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. All divergences were resolved by a third researcher. RevMan 5.4 software was used for Meta analysis. 【Results】 A total of 7 studies were included, involving 1 726 patients, 750 in the ThULEP group and 976 in the HoLEP group. Meta analysis showed that, compared with HoLEP group, the ThULEP group had shorter catheter indwelling time [MD=-0.10, 95%CI (-0.17--0.03), P=0.004] , shorter hospital stay [MD=-0.43, 95%CI (-0.60--0.25), P<0.000 01] , lower IPSS score 12 months after surgery [MD=-1.13, 95%CI (-1.95- -0.30), P=0.007] , lower QoL score 12 months after surgery [MD=-1.00, 95%CI (-1.19- -0.81), P<0.001] ,lower transfusion rate [OR=0.11, 95%CI (0.03-0.36), P=0.000 3] and lower incidence of urinary incontinence [OR=0.24, 95%CI (0.09-0.66), P=0.006] . 【Conclusion】 ThULEP may have similar efficacy and safety as HoLEP in the treatment of BPH, and has more advantages in some aspects.
