Efficacy of low intensity pulsed ultrasound in the treatment of erectile dysfunction
10.3969/j.issn.1009-8291.2023.11.005
- VernacularTitle:低强度脉冲式超声波治疗勃起功能障碍的疗效评价
- Author:
Jing WANG
1
;
Guohai SUN
1
;
Yang XU
1
;
Xiaozhi ZHAO
1
;
Yutian DAI
1
;
Zhipeng XU
1
Author Information
1. Department of Andrology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210009, China
- Publication Type:Journal Article
- Keywords:
erectile dysfunction;
low intensity pulsed ultrasound;
color duplex Doppler ultrasonography;
adverse effects;
sex life log question (CAQ);
International Erectile Index Score (IIF-EF)
- From:
Journal of Modern Urology
2023;28(11):936-941
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the efficacy of low intensity pulsed ultrasound (LIPUS) in the treatment of erectile dysfunction (ED). 【Methods】 A total of 121 ED patients treated during June 2020 and June 2022 were selected as the research objects. According to the International Erectile Index Score (IIEF-EF), the patients were divided into three subgroups:mild (17-25 points), moderate (11-16 points), and severe (0-10 points). The total effective rate, erectile hardness scale (EHS), sex life log questions (SEP), general assessment questionnaire (GAQ), peak systolic velocity (PSV), end diastolic velocity (EDV), and adverse reactions of the three groups before treatment, 4 weeks and 12 weeks after treatment were analyzed. 【Results】 A total of 119 patients completed the follow-up. There were significant increases in IIEF-EF and EHS at week 4 and 12 (P<0.05), and the total effective rate was 69.75% and 76.47%, respectively. The total effective rate was significantly higher in the mild and moderate groups than in the severe group at week 4 and 12 (P<0.05). The patients who answered "yes" to SEP2 and SEP3 accounted for 91.60% and 71.43%, respectively at week 4, and 92.44% and 78.15% at week 12, both significantly higher than the rates before treatment (52.10% and 27.73%, P<0.05). The proportion of patients who answered "yes" to GAQl and GAQ2 at week 4 were 84.87% and 71.43%, respectively, and were 82.35% and 70.59% respectively at week 12, with no significant difference. The PSV level significantly increased at week 12 compared to that before treatment [(48.85±14.11) cm/s vs. (41.42±14.90) cm/s] (P<0.05), while the EDV level significantly decreased [(-0.57±7.01) cm/s vs. (2.25± 5.68)cm/s] (P<0.05). 【Conclusion】 LIPUS can improve erectile function in ED patients without obvious adverse reactions.
