Single-center experience with vascularized adrenal displacement for the treatment of primary bilateral macronodular adrenal hyperplasia
10.3969/j.issn.1009-8291.2023.12.008
- VernacularTitle:带蒂肾上腺背部皮下移位术治疗原发性双侧大结节性肾上腺增生的单中心经验
- Author:
Yangyang SUN
1
;
Ziying WANG
1
;
Tao ZHENG
1
;
Fan YANG
1
;
Jing LIAN
1
;
Rui WANG
1
;
Weixing ZHANG
1
;
Tianbiao ZHANG
1
Author Information
1. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
- Publication Type:Journal Article
- Keywords:
adrenal gland;
primary bilateral macronodular adrenal hyperplasia;
Cushing syndrome;
vascularized adrenal displacement;
cortisol;
single-center experience
- From:
Journal of Modern Urology
2023;28(12):1042-1045
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore a new treatment of primary bilateral macronodular adrenal hyperplasia (PBMAH) and its efficacy. 【Methods】 Clinical data of 20 PBMAH patients treated in our hospital during Mar.2010 and Apr.2021 were retrospectively analyzed. All patients underwent laparoscopic subcutaneous displacement of vascularized adrenal. The clinical symptoms, plasma free cortisol, adrenocorticotrophic hormone (ACTH), and 24 h urinary free cortisol were regularly monitored after surgery. 【Results】 Of all 20 patients, 19 were followed up for 18 to 120 months (median 60 months). Three months after surgery, reexamination showed 1 patient had decreased plasma free cortisol and increased ACTH, but had no symptoms of low corticosteroids. After another 3 months, the plasma free cortisol and ACTH returned to normal. After 4 to 48 months, the parameters recovered in all patients and the clinical symptoms disappeared. 【Conclusion】 Laparoscopic vascularized adrenal displacement is a new and effective method for the treatment of PBMAH. It can alleviate the Cushing syndrome with no obvious adverse reactions.
