Clinical features and optimal treatment of primary urethral carcinoma
10.3969/j.issn.1009-8291.2023.12.002
- VernacularTitle:探讨原发性尿道癌的临床特点及最佳治疗方法
- Author:
Hanwei KE
1
;
Lin ZHU
1
;
Qi WANG
1
;
Xiaopeng ZHANG
1
;
Kexin XU
1
Author Information
1. Department of Urology, Peking University People’s Hospital, Peking University Applied Lithotripsy Institute, Beijing 100044, China
- Publication Type:Journal Article
- Keywords:
primary urethral carcinoma;
female;
urethral cancer radical surgery;
bladder preservation;
urinary obstruction
- From:
Journal of Modern Urology
2023;28(12):1013-1017
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the clinical features and treatment outcomes of female urethral carcinoma so as to improve the awareness and prognosis of this rare malignant disease. 【Methods】 Clinical data of 8 cases of female urethral carcinoma treated during Jan. 2012 to Dec.2022 at the Department of Urology of Peking University People’s Hospital were retrospectively analyzed. The patients underwent urodynamic tests, cystourethroscopy and pathological biopsy to confirm the diagnosis. Traditional radical surgery was performed in 5 cases, and radical surgery for lower urethral cancer with bladder preservation was performed in 3 cases. 【Results】 The patients aged 36 to 68 years, with a mean of 53.75 years. Urinary obstruction, lower urinary tract symptoms and urethral masses were common manifestations. Urodynamic tests indicated bladder outlet obstruction. After surgical treatment, radical surgery for lower urethral cancer with bladder preservation showed advantages over traditional radical surgery in terms of intraoperative bleeding, operation time and postoperative hospital stay. 【Conclusion】 Female primary urethral carcinoma is rare but invasive. Early diagnosis and radical surgery are crucial for improving the prognosis. Radical surgery for lower urethral cancer with bladder preservation has better treatment outcomes and postoperative quality of life compared to traditional radical surgery. For such patients, symptoms should be closely monitored and timely diagnosis and treatment should be performed.
