Influence factors of bone mineral density and its correlation with insulin resistance in obese children in Qianjiang area
10.3969/j.issn.1006-2483.2024.01.033
- VernacularTitle:湖北潜江地区肥胖儿童骨密度影响因素及与胰岛素抵抗水平的相关性分析
- Author:
Chao ZHANG
1
;
Hui LUO
1
;
Bo HOU
2
Author Information
1. Department of Pediatrics , Jianghan Oilfield General Hospital , Qianjiang , Hubei 433100 , China
2. Department of Endocrinology , Jianghan Oilfield General Hospital , Qianjiang , Hubei 433100 , China
- Publication Type:Journal Article
- Keywords:
Children;
Obesity;
Bone mineral density;
Insulin resistance
- From:
Journal of Public Health and Preventive Medicine
2024;35(1):141-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of bone mineral density (BMD) in obese children in Qianjiang area and analyze the correlation between BMD and insulin resistance. Methods The data on pediatric cases from the outpatient department of Jianghan Oilfield General Hospital in Qianjiang from January 2018 to December 2022 were collected. A total of 183 obese children who met the inclusion and exclusion criteria were included in the study and selected in the observation group. A total of 352 children undergoing physical examination during the same period were selected as the control group. Results The body mass, waist circumference, waist to hip ratio, and BMI of obese children were significantly higher than those of the control group (P<0.001). Biochemical indexes including FBG, FINS, Home-IR, ALP, and LDL-C in obese children were significantly higher than those in the control group (P<0.05), while bone mineral density, Ca, P, sOC and HDL-C were significantly lower than those in the control group (P<0.001). The bone mineral density of obese children was significantly correlated with their exercise intensity, sunshine exposure duration, sitting time, intake of milk and dairy products, intake of sweets, supplementation of trace elements, BMI, Home-IR, and sex (all P<0.05). BMI, Home-IR, sex, exercise intensity, and sunshine exposure length were independent risk factors affecting bone mineral density of obese children (all P<0.05). Bone mineral density was negatively correlated with BMI and Home-IR (P=0.028 and0.017, respectively), and positive correlation with exercise intensity and sunlight exposure (P=0.033). Conclusion BMD of obese children in Qianjiang area is affected by gender, body mass index, diet, vitamin intake, and physical activity, and is negatively correlated with insulin resistance. Home-IR can be used as a reference for screening BMD of obese children.
