99m Technetium Pertechnetate Thyroid Scan for remnant thyroid tissue detection among post-thyroidectomy patients at Jose R. Reyes Memorial Medical Center: A retrospective analysis
- Author:
Athena Charisse S. Ong
1
;
Marcelino A. Tanquilut
1
;
Wenceslao S. Llauderes
1
;
Emelito O. Valdez-Tan
1
;
Ivan Ray F. David
1
Author Information
1. Department of Nuclear Medicine, Jose R. Reyes Memorial Medical Center
- Publication Type:Journal Article
- Keywords:
99m Tc-pertechnetate scan;
131I post-therapy scan;
Thyroid remnants
- MeSH:
Thyroid Neoplasms
- From:
The Philippine Journal of Nuclear Medicine
2022;17(2):36-42
- CountryPhilippines
- Language:English
-
Abstract:
This study aims to determine the diagnostic value of a 99mTc-pertechnetate (99m TcO-4) thyroid scan among
patients with DTC who underwent thyroidectomy to assess functioning thyroid remnants before radioactive
iodine therapy. A retrospective non-experimental cross-sectional design was done to compare the results of the
99m TcO-4 thyroid scan with the patient's post-RAI scan. A review of all our patients' charts was done for eight
years, and after excluding those that did not fit the criteria, 70 patients were included in the study. Data
collected was analyzed on a "per patient" basis– where patients either had a "positive scan" or "negative scan",
and on a "per lesion" basis – where every lesion's presence and size were compared on both modalities.
99m TcO-4 thyroid scan in the "per patient" analysis showed a sensitivity of 73.91%, specificity of 100%, positive
predictive value (PPV) or 100%, and accuracy of 74.29%, however, negative predictive value was determined to
be 5.26%. In the "per lesion" analysis, the scan had a less favorable performance with the computed sensitivity
of 61.69%, PPV of 94.93%, and accuracy at 59.41%. It was then concluded that 99mTc-pertechnetate scan may
be useful in determining functioning remnant thyroid tissue and subsequent management of DTC patients after
thyroidectomy, but must take note of its low negative predictive value.
- Full text:17 (2) article 3.pdf
