Correlation analysis of body composition and thyroid function in different genders of T2DM based on propensity score matching
- VernacularTitle:基于倾向值匹配的2型糖尿病患者不同性别中体成分与甲状腺功能的相关性分析
- Author:
Ruo ZHANG
1
;
Chunhong ZHANG
1
;
Shimei DING
1
;
Yang JIAO
1
;
Junhong LONG
1
;
Jing XU
1
Author Information
- Publication Type:Journal Article
- Keywords: type 2 diabetes mellitus; euthyroidism; thyroid hormones; body composition analysis; propensity score matching
- From: Journal of Xi'an Jiaotong University(Medical Sciences) 2023;44(6):930-937
- CountryChina
- Language:Chinese
- Abstract: 【Objective】 To investigate the correlation between body composition and thyroid function indicators in type 2 diabetic patients with euthyroidism of different genders. 【Methods】 Type 2 diabetic patients with euthyroidism who were hospitalized in the Endocrinology Department of The Second Affiliated Hospital of Xi’an Jiaotong University from February 2016 to September 2018 were enrolled in this study. Bioelectric impedance analysis was used to measure body composition, and the thyroid function indicators (FT3, FT4, and TSH) were tested. The male and female subjects were matched according to the ratio of 2:1 using the propensity score matching method, and the correlation between body composition and thyroid function indicators was studied in different genders by correlation analysis. 【Results】 The basal metabolic rate, trunk fat mass, fat-free mass, fat-free mass index, bone mass, water mass, total body muscle mass, skeletal muscle mass, and skeletal muscle index were positively correlated with FT3 in male patients (P<0.05). The percentage of body fat mass and fat mass index were positively correlated with FT3 and TSH (P<0.05), and the percentages of lean mass, water mass, and total body muscle mass were negatively correlated with FT3 and TSH (P<0.05), and the basal metabolic rate was negatively correlated with FT4 (P<0.05) in female. 【Conclusion】 In euthyroid type 2 diabetic patients, the correlation between body composition and thyroid function indicators are different between males and females. In males, only FT3 is positively correlated with basal metabolic rate, trunk fat mass, and fat free-related composition; while in females, both FT3 and TSH are positively correlated with fat-related composition, but negatively correlated with fat-free-related composition.
