Visual analysis of literature on intestinal flora and bone metabolism by Citespace
- VernacularTitle:基于Citespace胃肠道菌群与骨代谢相关文献研究的可视化分析
- Author:
Zhangkai ZHAO
1
;
Wantao DONG
1
,
2
;
Jianhong WANG
1
;
Rumeng CHANG
1
;
Jie ZHANG
1
;
Pan YANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Citespace; gut microbiota; bone metabolism; visual analysis of literature; immunity
- From: Journal of Xi'an Jiaotong University(Medical Sciences) 2023;44(2):315-322
- CountryChina
- Language:Chinese
- Abstract: 【Objective】 To analyze the literature on the relationship between gut microbiota and bone metabolism, identify the current research hotspots and difficulties, and provide research ideas and directions for the clinical prevention and treatment of bone metabolism related diseases. 【Methods】 Based on the Citespace literature visualization analysis software, the co-occurrence and cluster analysis of keywords and other information of the included 394 literatures were performed, and the visual map was drawn. 【Results】 Among the included literatures, the keywords such as inflammatory bowel disease, T cells, dendritic cells, short-chain fatty acids, and chronic kidney disease appeared with high frequency. The cluster of intestinal alkaline phosphatase, metabolic osteoarthritis, dendritic cells, and signaling pathway was the current research hotspot. Recent years have witnessed a rapid increase in published articles in this field, with the United States as the leading origin. 【Conclusion】 The mechanism by which gut microbiota interferes with the immune system and regulates bone metabolism to maintain bone homeostasis is still the core of current research.
