Factors That Affect Stent-Related Complications in Patients with Malignant Obstruction of the Esophagus or Gastric Cardia.
- Author:
Hiroyasu IWASAKI
1
;
Takashi MIZUSHIMA
;
Yuta SUZUKI
;
Shigeki FUKUSADA
;
Kenta KACHI
;
Takanori OZEKI
;
Kaiki ANBE
;
Hironobu TSUKAMOTO
;
Fumihiro OKUMURA
;
Takashi JOH
;
Hitoshi SANO
Author Information
- Publication Type:Original Article
- Keywords: Esophageal stent; Risk factors; Complication; Radiation; Chemotherapy
- MeSH: Adenocarcinoma; Carcinoma, Squamous Cell; Cardia*; Constriction, Pathologic; Deglutition Disorders; Drug Therapy; Esophagus*; Fistula; Humans; Retrospective Studies; Risk Factors; Stents
- From:Gut and Liver 2017;11(1):47-54
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Self-expandable metallic stent (SEMS) placement is effective for dysphagia that results from malignant obstruction of the esophagus or gastric cardia; however, stent-related complications may be life-threatening. Thus, the goal of this study was to identify risk factors associated with complications following esophageal stenting. METHODS: Of the 71 patients who underwent SEMS placement for dysphagia as a result of malignant stricture of the esophagus or gastric cardia, 53 patients with squamous cell carcinoma or adenocarcinoma, without previous SEMS placement, without a fistula, and without recurrent tumor after surgery were retrospectively identified. The occurrence of stent-related complications was used as an endpoint. RESULTS: Stent-related complications were identified in 26 patients (49.1%), and major complications occurred in 14 patients (26.4%). The use of an Ultraflex stent (odds ratio [OR], 6.81; 95% confidence interval [CI], 1.54 to 30.00; p=0.011) and prior chemotherapy (OR, 6.13; 95% CI, 1.46 to 25.70; p=0.013) were significantly associated with stent-related complications. Moreover, the use of an Ultraflex stent (OR, 19.60; 95% CI, 2.26 to 170.00; p=0.007) and prior radiation (OR, 25.70; 95% CI, 2.37 to 280.00; p=0.008) significantly increased the risk of major complications. CONCLUSIONS: The use of an Ultraflex stent and prior radiation and/or chemotherapy may represent risk factors for complications following esophageal SEMS placement.