Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy
10.3980/j.issn.1672-5123.2024.2.24
- VernacularTitle:不同程度非增殖性糖尿病视网膜病变的OCTA表现
- Author:
Menghuan DAI
1
;
Dongli LI
1
;
Yixin CUI
1
;
Lu SHEN
1
;
Qirui LI
1
;
Lingna RAO
1
;
Shurong GUO
1
;
Ling YUAN
1
Author Information
1. Department of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, China
- Publication Type:Journal Article
- Keywords:
non-proliferative diabetic retinopathy;
optical coherence tomography angiography(OCTA);
visual acuity;
macular foveal avascular area;
superficial capillary plexus;
deep capillary plexus
- From:
International Eye Science
2024;24(2):307-311
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the differences in varying stages of non-proliferative diabetic retinopathy(NPDR)using optical coherence tomography angiography(OCTA).METHODS: Cross-sectional study. A total of 77 cases(77 eyes)of diabetic patients were included, and they were divided into non-diabetic retinopathy(NDR; 23 eyes)and non-proliferative diabetic retinopathy(NPDR; 54 eyes)groups, further subdivided into mild NPDR(20 eyes), moderate NPDR(20 eyes), and severe NPDR(14 eyes). Foveal avascular zone(FAZ)area, superficial and deep capillary plexus densities(SSP and DSP), and visual acuity(LogMAR)were compared between NDR and NPDR groups. Furthermore, the visual acuity, FAZ area and levels of SSP and DSP were compared in different degrees of NPDR. Correlation analysis were conducted to elucidate relationships between FAZ area, visual acuity, SSP, DSP, and severity of the disease.RESULTS: Compared with the NDR group, the visual acuity(LogMAR)and macular FAZ area increased, while SSP and DSP were decreased in the NPDR group(P<0.05); there were significant differences in visual acuity, FAZ area and SSP and DSP levels in different degrees of NPDR(P<0.05). Visual acuity(LogMAR)and FAZ area displayed a positive correlation with the severity of disease, while SSP and DSP showed a negative correlation.CONCLUSION: With the progression of NPDR, the visual acuity(LogMAR)and FAZ area increased, and the SSP and DSP decreased.
