Matrix Metalloproteinase-9 Expression in Cerebral Ischemia (review)
- VernacularTitle:基质金属蛋白酶-9在脑缺血中的研究进展
- Author:
Hong XU
;
Hua SUN
- Publication Type:Journal Article
- Keywords:
matrix metalloproteinase-9, cerebral ischemia, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2012;18(12):1127-1130
- CountryChina
- Language:Chinese
-
Abstract:
The expression of matrix metalloproteinase-9 (MMP-9) after cerebral ischemia reperfusion injury can accelerate the damage of brain-blood barrier and plays an important role in brain edema after cerebral hemorrhage. The level of MMP-9 can reflex the severity of brain ischemia, indicate to the volume of infarct area and point out the prognosis of the disease. This article reviewed its source and expression,the gene regulation and polymorphism, hemorrhage transformation and nhibitors, and the mechanism was also analyzed.
