Lung transplantation after paraquat poisoning in an adolescent: one case report and literature review
10.3969/j.issn.1674-7445.2023175
- VernacularTitle:青少年百草枯中毒后肺移植1例并文献复习
- Author:
Fanjie MENG
1
;
Yan ZHANG
1
;
Hongfei CAI
1
;
Fanyu MENG
1
;
Rui WANG
1
;
Youbin CUI
1
;
Jingyu CHEN
2
;
Yang LI
1
Author Information
1. Department of Thoracic Surgery, the First Bethune Hospital of Jilin University, Changchun 130021, China.
2. .
- Publication Type:OriginalArticle
- Keywords:
Lung transplantation;
Paraquat poisoning;
Pulmonary fibrosis;
Respiratory failure;
Extracorporeal membrane oxygenation;
Infection;
Passenger lymphocyte syndrome;
Bronchial stenosis
- From:
Organ Transplantation
2024;15(1):112-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the effect of the timing of lung transplantation and related treatment measures on clinical prognosis of patients with paraquat poisoning. Methods Clinical data of a patient with paraquat poisoning undergoing bilateral lung transplantation were retrospectively analyzed. Clinical manifestations, auxiliary examination, diagnosis and treatment of this patient were summarized and analyzed. Results A 17-year-old adolescent was admitted to hospital due to nausea, vomiting, cough and systemic fatigue after oral intake of 20-30 mL of 25% paraquat. After symptomatic support treatment, the oxygen saturation was not improved, and pulmonary fibrosis continued to progress. Therefore, sequential bilateral lung transplantation was performed under extracorporeal membrane oxygenation (ECMO). After postoperative rehabilitation and active prevention and treatment for postoperative complications, the patient was discharged at postoperative 50 d. Conclusions The timing of lung transplantation after paraquat poisoning may be selected when the liver and kidney function start to recover. Active and targeted prevention of potential pathogen infection in perioperative period and early rehabilitation training contribute to improving clinical prognosis of lung transplant recipients.
