Optimal diagnosis and treatment for renal allograft fibrosis
10.3969/j.issn.1674-7445.2023156
- VernacularTitle:移植肾纤维化的诊断和治疗优化方案
- Author:
Haojun WANG
1
;
Zejia SUN
1
;
Wei WANG
1
Author Information
1. Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
- Publication Type:ExpertForum
- Keywords:
Kidney transplantation;
Complication;
Renal fibrosis;
Biomarker;
Chronic rejection;
Immunosuppression;
Stem cell therapy;
Gene therapy
- From:
Organ Transplantation
2024;15(1):19-25
- CountryChina
- Language:Chinese
-
Abstract:
Renal allograft fibrosis is one of the common and severe complications after kidney transplantation, which seriously affects the function and survival rate of renal allograft, and may even lead to organ failure and patient death. At present, the researches on renal allograft fibrosis are highly complicated, including immunity, ischemia-reperfusion injury, infection and drug toxicity, etc. The diagnosis and treatment of renal allograft fibrosis remain extremely challenging. In this article, the latest research progress was reviewed and the causes, novel diagnosis and treatment strategies for renal allograft fibrosis were investigated. By improving diagnostic accuracy and optimizing treatment regimen, it is expected to enhance clinical prognosis of kidney transplant recipients, aiming to provide reference for clinicians to deliver proper management for kidney transplant recipients.
