Cognitive impairment and depression among breast cancer patients undergoing chemotherapy in a tertiary hospital
- Author:
Meleza Mea B. Cambalon-Ongco
1
;
Marissa T. Ong
1
Author Information
- Publication Type:Journal Article
- MeSH: Cognitive Dysfunction; Depression; Breast Neoplasms; Mental Status and Dementia Tests
- From: Philippine Journal of Neurology 2023;26(2):42-53
- CountryPhilippines
- Language:English
-
Abstract:
Background:Breast cancer is the leading cause of cancer death among women worldwide. Studies showed
conflicting results regarding presence of cancer, cancer treatment, and its association with
dementia. Likewise, depression is often associated with cognitive problems.
Objectives:This study aims to determine the prevalence and association of cognitive impairment and depression among breast cancer patients
Methods:This is a prospective cross-sectional study utilizing Montreal Cognitive Assessment – Philippines (MOCA-P) and Patient Health Questionnaire (PHQ-9) Filipino version questionnaires through face-to-face interview. In analyzing the presence of cognitive impairment and depression, Chi-square was performed; all significant factors from this test underwent binary logistic regression to ascertain the statistical effect size for the presence of cognitive impairment and depression.
Results:Results showed that 80.8% (97 out of 120 patients) have cognitive impairment while 27.5% of the patients have depression. Among the patients with cognitive impairment, 24.2% of them had depression. Results also showed significant association between the level of education and MOCA-P score suggesting that the higher the level of education, the better the MOCA-P score. This study showed no significant association between presence of cognitive impairment and depression.
Conclusion:In analyzing and managing patients with cognitive impairment, the level of educational attainment should be put into consideration since it is correlated significantly with MOCA-P results. As such, concomitant depression should be addressed accordingly since it may affect the patients’ overall health status. - Full text:PJneurology 4.pdf
