Correlation between malignant tumors and ABO blood types in Chaoshan area, Guangdong
10.13303/j.cjbt.issn.1004-549x.2023.03.015
- VernacularTitle:广东潮汕地区恶性肿瘤与ABO血型的相关性分析
- Author:
Binliang HUANG
1
;
Zhaomin XIE
1
,
2
;
Dan WANG
3
;
Wanli WU
1
;
Heyan WANG
4
;
Yiwei XU
1
;
Fangcai WU
1
Author Information
1. Cancer Hospital of Shantou University Medical College, Shantou 515000, China
2. School of Public Health, Shantou University Medical College
3. Shantou Central Hospital
4. Shantou Central Blood Station
- Publication Type:Journal Article
- Keywords:
ABO blood type;
malignant tumor;
risk factor
- From:
Chinese Journal of Blood Transfusion
2023;36(3):254-257
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the relationship between ABO blood types and the risk of malignant tumors in Chaoshan area, Guangdong. 【Methods】 Chi-square test was used to analyze the distribution of ABO blood types between 45 890 patients with malignant tumors from the Cancer Hospital of Shantou University Medical College and 42 465 healthy blood donors from Shantou Central Blood Bank. 【Results】 Among the main types of malignant tumors, the distributions of ABO blood types in patients with esophageal cancer or head and neck cancer were significantly different from that in the normal population (χ2=11.16, P<0.05; χ2=74.36, P<0.05; respectively). People with type B were identified with high risk of esophageal cancer and head and neck cancer (OR=1.09, 95% CI=1.03-1.15, P<0.05; OR=1.46, 95% CI=1.34-1.60, P<0.05), whereas those with type A or O were identified with low risk of head and neck cancer (OR=0.87, 95% CI=0.79-0.96, P<0.05; OR=0.83, 95% CI=0.76-0.90, P<0.05). 【Conclusion】 ABO blood type distribution in patients with esophageal cancer or head and neck cancer in Chaoshan area may be different from that in normal population, suggesting that different ABO blood types may be associated with the risk of esophageal cancer and head and neck cancer.
