A Case Report of Annular Elastolytic Giant Cell Granuloma
10.12376/j.issn.2097-0501.2023.02.015
- VernacularTitle:环状弹性纤维溶解性巨细胞肉芽肿一例
- Author:
Zusha QIAO
1
;
Hongzhong JIN
2
,
3
Author Information
1. Department of Dermatology, Second Hospital of Shanxi Medical University, Taiyuan 030001, China.
2. Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
3. Peking Union Medical College, Beijing 100730, China.
- Publication Type:Journal Article
- Keywords:
annular plaque;
plaque granuloma;
multinuclear giant cell;
elastosis
- From:
JOURNAL OF RARE DISEASES
2023;2(2):285-289
- CountryChina
- Language:Chinese
-
Abstract:
Annular elastolytic giant cell granuloma(AEGCG) is a rare granulomatous skin condition. We present a case of a 67-year-old man with annular plaques on the face, neck, shoulder, back and upper limbs, and mildly pruritis exceeding one year. Histopathological examination demonstrated granulomatous inflammatory infiltration of lymphocytes, histiocytes and multinuclear giant cells in the middle and the upper dermis, with more local eosinophils. Elastic fiber staining showed that elastic fibers were absent in granuloma area and were engulfed by multinucleated giant cells. Based on the clinical and histopathological findings, a diagnosis of AEGCG was made. The etiology and pathogenesis of this condition are unclear, and atypical manifestations of non-exposed areas can also occur.It is usually related to systemic diseases lacks specific treatment at present.
