A Case of Chronic Myelomonocytic Leukemia: the Onset of which was Manifestedby Hypokalemia and Hypocalcemia
10.12376/j.issn.2097-0501.2022.04.014
- VernacularTitle:以顽固性低钾、低钙血症为主要起病表现的慢性粒-单核细胞白血病一例
- Author:
Weimin HAN
1
;
Xiaoli CHANG
1
;
Ronghua HU
1
;
Wanling SUN
1
Author Information
1. Department of Hematology, Xuanwu Hospital Capital, Medical University, Beijing 100053, China.
- Publication Type:Journal Article
- Keywords:
chronic myelomonocytic leukemia;
hypokalemia;
hypocalcemia
- From:
JOURNAL OF RARE DISEASES
2022;1(4):446-448
- CountryChina
- Language:Chinese
-
Abstract:
Intractable hypokalemia and hypocalcemia are rare complications in leukemia patients. This article reports a patient with chronic myelomonocytic leukemia (CMML)with refractory hypokalemia, hypocalcemia, hypochloridemia, hypomagnesemia-a 48-year-old man complained of fatigue, nausea, and face numbness for over one month. The number of monocytosis in peripheral blood and bone marrow increased remarkably. At the same time, the patient developed hypokalemia, hypochloridemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, massive proteinuria, and increase in plasma aldosterone and renin. After two coursea of treatment using Azacitidine therapy, complete remission of bone marrow was achieved and the electrolyte disturbance was almost corrected, except hypomagnesemia. We summarize the clinical characteristics of the patient so as to raise the clinical awareness of such cases.
