A Young Hemophilia Patient with Advanced Hemophilic Arthritis and HIV Infection
10.12376/j.issn.2097-0501.2022.04.008
- VernacularTitle:晚期关节病变合并HIV感染的青年血友病患者
- Author:
Huacong CAI
1
,
2
;
Bin FENG
2
,
3
;
Wei CAO
2
,
4
;
Shufen LIU
2
,
5
;
Tao YUAN
2
,
6
;
Yan ZHANG
2
,
7
;
Kuixing LI
1
,
2
;
Yongqiang ZHAO
1
,
2
;
Shujie WANG
1
,
2
Author Information
1. Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
2. Peking Union Medical College, Beijing 100730, China.
3. Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
4. Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
5. Department of Physical Medicine and Rehabilitation, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
6. Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
7. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
- Publication Type:Journal Article
- Keywords:
hemophilia;
arthritis;
HIV;
osteoporosis
- From:
JOURNAL OF RARE DISEASES
2022;1(4):407-412
- CountryChina
- Language:Chinese
-
Abstract:
A young male diagnosed with severe hemophilia A since childhood, was presented with recurrent joint and urinary bleeding. Annualized bleed rates dropped below five with low dose prophylactic medication.Bleeding in the right knee joint recently aggravated. Due to coexisting HIV infection and advanced hemophilic arthritis, the patient was managed by a multi-disciplinary team(MDT).Total knee arthroplasty was performed by an experienced surgeon using modern prosthesis design and intraoperative navigation technologies.Physical and rehabilitation therapy was provided during the postoperative period, and joint function improved. The MDT managed the young patient with HIV infection and advanced hemophilic arthritis. The patient was diagnosed with osteoporosis thought to have been caused by hemophilia, HIV infection and antiviral drugs; and he received treatment. The treatment of this patient reflects the importance of multidisciplinary cooperation in the management of difficult and rare diseases.
