Pathogenesis based Precision Therapy for Inborn Errors of Immunity
10.12376/j.issn.2097-0501.2022.03.004
- VernacularTitle:免疫出生错误基于发病机制的精准治疗
- Author:
Zhou SHU
1
;
Huawei MAO
2
Author Information
1. Department of Immunology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
2. Department of Immunology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.Key Laboratory of Major Diseases in Children of Ministry of Education, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
- Publication Type:Journal Article
- Keywords:
inborn errors of immunity;
pathogenesis;
precision therapy
- From:
JOURNAL OF RARE DISEASES
2022;1(3):245-251
- CountryChina
- Language:Chinese
-
Abstract:
Precision medicine aims at using target therapy on specific diseases by studying the pathogenesis and finding biomarkers. Inborn errors of immunity (IEI) are caused by single gene mutations, providing the perfect human models to study immunology. The technology rapidly developes recently, so scientists have a deeper understandings of the phenotypes, genotypes, and the biological targets, so that doctors are able to use precision medicine on IEIs with many successful cases. The precision medicine have advantages in the treatment of pathogenesis of diseases. This article summarizes successful cases of using precision medicine for IEI recently.
