Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis
10.12376/j.issn.2097-0501.2023.03.018
- VernacularTitle:黏多糖贮积症眼部并发症的诊疗进展
- Author:
Meipan SHI
1
;
Caiping SHI
2
;
Chixin DU
1
Author Information
1. Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
2. Department of Ophthalmology, Children′s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
- Publication Type:Review
- Keywords:
mucopolysaccharidosis;
ocular complications;
diagnosis;
treatment
- From:
JOURNAL OF RARE DISEASES
2023;2(3):450-454
- CountryChina
- Language:Chinese
-
Abstract:
Mucopolysaccharidosis is a series of rare diseases where a lack of an enzyme affecting mucopolysaccharides metabolism in the patients′ lysosome induces the intracellular deposition of the mucopolysaccharides, and causes ocular and organ-related complications. Ocular complications included corneal opacity, glaucoma, ametropia, strabismus, and chorioretinopathy. This review summarizes the mechanisms, clinical manifestations, specific ophthalmological examinations, and treatments for offering the ophthalmological knowledge to diagnose and begin treatment earlier.
