A Survey of the Current Status of Surgical Treatment of Hemophilic Osteoarthropathy in China Mainland 17 Grade A General Hospitals

Yiming XU; Huiming Peng; Shuaijie Lyu; Peijian Tong; Hu LI; Fenyong Chen; Haibin Wang; Qi Yang; Bin Chen; Zhen Yuan; Rongxiu BI; Jianmin Feng; Wenxue Jiang; Zongke Zhou; Meng Fan; Xiang LI; Guanghua Lei; Xisheng Weng

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A Survey of the Current Status of Surgical Treatment of Hemophilic Osteoarthropathy in China Mainland 17 Grade A General Hospitals

VernacularTitle:中国大陆地区17家三甲综合医院血友病性骨关节病外科治疗现状调查
Author: Yiming XU ^{1
,

2} ; Huiming PENG ^{1
,

2} ; Shuaijie LYU ³ ; Peijian TONG ³ ; Hu LI ⁴ ; Fenyong CHEN ⁵ ; Haibin WANG ⁶ ; Qi YANG ⁷ ; Bin CHEN ⁸ ; Zhen YUAN ⁹ ; Rongxiu BI ¹⁰ ; Jianmin FENG ^{1
,

11} ; Wenxue JIANG ^{1
,

12} ; Zongke ZHOU ^{1
,

13} ; Meng FAN ^{1
,

14} ; Xiang LI ^{1
,

15} ; Guanghua LEI ^{1
,

16} ; Xisheng WENG ^{1
,

2}
Author Information

1. Department of Orthopaedic Surgery, Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Key Laboratory of Big Data for Spinal Deformities, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
2. Peking Union Medical College, Beijing 100730, China.
3. Department of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.
4. Department of Orthopedics, Peking University People′s Hospital, Beijing 100044, China.
5. Department of Orthopedics, Fujian Medical University Union Hospital, Fuzhou 350001, China.
6. Department of Orthopedics, Guangzhou University of Chinese Medicine First Hospital, Guangzhou 510405, China.
7. Department of Orthopedics, Harbin First Hospital, Harbin 150010, China.
8. Department of Orthopedics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
9. Department of Orthopedics, the First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), Jinan 250014, China.
10. Department of Orthopedics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, China.
11. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
12. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, Shenzhen Hyzen Hospital, Shenzhen 518000, China.Department of Orthopedics, Shenzhen Ren′an Hospital, Shenzhen 518116, China.Department of Orthopedics, the Third People′s Hospital of Shenzhen, Shenzhen 518112, China.
13. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
14. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, Tianjin First Central Hospital, Tianjin 300384, China.
15. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, PLA General Hospital, Beijing 100853, China.
16. Peking Union Medical College, Beijing 100730, China.Department of Orthopedics, Xiangya Hospital Central South University, Changsha 410008, China.
Publication Type:Journal Article
Keywords: hemophilia; hemophilic osteoarthropathy; surgery; questionnaire survey
From: JOURNAL OF RARE DISEASES 2023;2(4):516-522
CountryChina
Language:Chinese
Abstract: Objective To understand the current status of surgical treatment for hemophilia osteoarthropathy (HO) in China. Methods Using an online questionnaire, select domestic hospitals that partici-pated in the compilation of the 'Guideline for perioperative management of hemophilia patients undergoing orthopaedic surgery in China ', in addition to members of the National Joint Surgery Group, and the Orthopedic Branch of the Chinese Medical Association for targeted investigation and analysis. Results A total of 17 domestic hospitals were included, all of which were general hospitals. Hospitals that started HO surgery treatment before 2000 accounted for 35.29%. A total of 3057 surgical cases of HO were reported by those hospitals. The most commonly performed surgical procedures were hip and knee joint replacement. The most commonly used coagulation factor replacement regimen was recombinant coagulation factor preparation. Ten hospitals reported finding patients with transfusion-related infectious diseases. Bleeding and hematoma formation were the most frequently reported surgical complications. Excessive length of hospital stay and high economic costs were the most frequently reported problems. Conclusions Surgical treatment for HO in 17 hospitals is mainly carried out in some large comprehensive medical centers in the eastern region. Compared with the patient base, the popularity and number of surgeries are still relatively insufficient. It is necessary to further standardize the treatment system by standardizing factor replacement and strengthening rehabilitation to improve surgical treatment outcomes.