Clinical Features, Diagnosis and Management of Fibrodysplasia Ossificans Progressiva
10.12376/j.issn.2097-0501.2023.04.006
- VernacularTitle:进行性骨化性纤维发育不良的临床特点及诊治
- Author:
Junduo ZHAO
1
,
2
;
Jianxiong SHEN
1
,
2
Author Information
1. Department of Orthopaedic Surgery, Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &
2. Peking Union Medical College, Beijing 100730, China.
- Publication Type:Journal Article
- Keywords:
fibrodysplasia ossificans progressiva;
heterotopic ossification;
rare diseases
- From:
JOURNAL OF RARE DISEASES
2023;2(4):501-508
- CountryChina
- Language:Chinese
-
Abstract:
Fibrodysplasia ossificans progressiva(FOP) is a rare congenital disease characterized by progressive heterotopic ossification, causing severe immobility with multi-system involvement. The relatively low incidence rate and incomplete knowledge among clinicians of the disease often result in misuse of invasive procedures or surgical treatment, leading to the progression of heterotopic ossification. To promote the knowledge of FOP, this article presents a comprehensive review involving epidemiology, pathological mechanisms, clinical features, diagnosis, and management of the FOP.
