Effect of intraoperative cell salvage on allogeneic blood transfusion requirements, coagulation function and electrolytes in postpartum hemorrhage of cesarean section
10.13303/j.cjbt.issn.1004-549x.2023.01.008
- VernacularTitle:自体血回输对剖宫产产后出血患者的异体输血需求与凝血功能及电解质的影响
- Author:
Huageng HUANG
1
;
Xuelian RAN
1
;
Yanjuan HUANG
1
;
Kejian LU
1
;
Bairong HU
2
Author Information
1. Department of Anesthesiology, The Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China
2. Department of Anesthesiology, Nanning Second Maternal and Child Health Hospital
- Publication Type:Journal Article
- Keywords:
postpartum hemorrhage;
intraoperative cell salvage;
allogeneic blood transfusion;
coagulation function;
electrolyte
- From:
Chinese Journal of Blood Transfusion
2023;36(1):32-35
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the effect of intraoperative cell salvage on allogeneic blood transfusion requirements, coagulation function and electrolytes in postpartum hemorrhage patients. 【Methods】 A study on postpartum hemorrhage patients undergoing cesarean section in the Third Affiliated Hospital of Guangxi Medical University form September 2016 to May 2022 was conducted retrospectively. A total of 137 patients were enrolled and divided into experimental group (n=70) and control group (n=67) according to whether intraoperative cell salvage was used during operation. The blood loss, proportion and volume of allogeneic red blood cells (RBCs) and coagulation component transfusion, hemoglobin (Hb) level, coagulation function, electrolyte, the incidence of complications, proportion of ICU admission, ICU stay and in-hospital stay were compared between the two groups. 【Results】 The proportion of patients receiving allogeneic RBCs in the experimental group and in the control group was 31.4% vs 100.0% (P<0.05). The experimental group also had lower use of plasma (31.4% vs 53.7%, P<0.05). The postoperative 24 h of activated partial thromboplastin time (APTT) and prothrombin time (PT) in the two groups was longer than preoperative, and APTT in the control group did not recover at discharge (P<0.05). Fibrinogen (Fib) decreased postoperative 24 h in the two groups (P<0.05). The blood calcium in the two groups decreased 30 minutes after operation, but the decrease in the experimental group was slight, and two groups did not recover 24 h after operation (P<0.05). There was no statically significant difference in blood loss, volume of allogeneic RBCs and coagulation component transfusion, Hb level, incidence of complications, the proportion of ICU admission, ICU stay and in-hospital stay (P>0.05). 【Conclusion】 This study demonstrated that intraoperative cell salvage could reduce the requirement for allogeneic RBCs without compromising coagulation function in postpartum hemorrhage patients undergoing cesarean section, but the changes of calcium need to be concerned after transfusion.
