Frequency of double population of Rh blood group C and E antigen after transfusion of allogeneic red blood cells and its influence on blood transfusion efficacy
10.13303/j.cjbt.issn.1004-549x.2023.01.007
- VernacularTitle:输注异体红细胞后Rh血型C、E抗原双群频率及其对输血效果的影响
- Author:
Xiaomin FENG
1
;
Yanling GE
1
Author Information
1. Department of Blood Transfusion, Beijing Jishuitan Hospital, Beijing 100035, China
- Publication Type:Journal Article
- Keywords:
RhC;
RhE;
double population
- From:
Chinese Journal of Blood Transfusion
2023;36(1):30-32
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To prove the necessity of precise red blood cell transfusion by studying the frequency of double population of Rh blood group C and E antigen after allogeneic red blood cell transfusion in our hospital and its influence on blood transfusion efficacy. 【Methods】 From June 2021 to March 2022, 296 blood recipients, transfused with ABO homogeneous but RhC/E phenotypes unknown 2U-RBC suspension, were enrolled from Beijing Jishuitan Hospital, and the ABO, RhD, RhC, RhE blood type before transfusion and double population frequency of C and E antigens after transfusion were detected. Patients with RhC and E not changed in comparison with pre-transfusion were set as group A(n=135), with RhC becoming double population as group B (n=18), with RhE becoming double population as group C (n=116), and with both RhC and RhE changed to double population as group D(n=27). The levels of red blood cell (RBC), haemoglobin (Hb) and hematocrit (HCT) before and after blood transfusion were compared among the four groups. 【Results】 The negative rates of RhD, RhC and RhE in 296 patients were 0.34%(1/296), 20.27%(60/296) and 67.57%(200/296), respectively. There were 17 cases out of positive screening for unexpected antibodies, among which 7 cases were of anti-E, with the highest proportion. After RBCs transfusion, the double population frequencies of C and E antigens were 15.20%(45/296) and 48.31%(143/296), respectively. The levels of RBC, Hb and HCT in group A, B, C and D were significantly increased, and the difference was statistically significant (P<0.05). There were significant differences in the elevations of RBC and HCT among the four groups (P<0.05), and the elevations of RBC, Hb and HCT were all group A > group C > group B> group D. 【Conclusion】 The Rh blood group C and E antigen double population has an significant influence on the efficacy of blood transfusion.
