HBV infection among blood donors from 18 domestic blood stations of prefecture-level cities

Dingding Wang; Youhua Shen; Jianling Zhong; Hui Zhang; Zhibin Tian; Lin Bao; Huixia Zhao; Jian Zhang; Peng Wang; Yanqin HE; Wei Zhang; Li LI; Hao LI; Dexu Chu; Ying Wang; Xin Zhang; Shouguang XU; Min Huang; Yan Qiu

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HBV infection among blood donors from 18 domestic blood stations of prefecture-level cities

VernacularTitle:我国18家地市级血站献血人群HBV感染情况分析
Author: Dingding WANG ¹ ; Youhua SHEN ² ; Jianling ZHONG ³ ; Hui ZHANG ⁴ ; Zhibin TIAN ⁵ ; Lin BAO ⁶ ; Huixia ZHAO ⁷ ; Jian ZHANG ⁸ ; Peng WANG ⁹ ; Yanqin HE ¹⁰ ; Wei ZHANG ¹¹ ; Li LI ¹² ; Hao LI ¹³ ; Dexu CHU ¹⁴ ; Ying WANG ¹⁵ ; Xin ZHANG ¹⁶ ; Shouguang XU ¹⁷ ; Min HUANG ¹⁸ ; Yan QIU ¹⁹
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1. Handan Blood Station, Handan 056001, China
2. Shangrao Blood Station
3. Xianyang Blood Station
4. Nanning Blood Station
5. Puyang Blood Station
6. Yichun Blood Station
7. Qingdao Blood Station
8. Yancheng Blood Station
9. Bijie Blood Station
10. Ganzhou Blood Station
11. Beijing Tongzhou Blood Station
12. Huaian Blood Station
13. Chengde Blood Station
14. Chifeng Blood Station
15. Baoding Blood Station
16. Xingtai Blood Station
17. Yangzhou Blood Station
18. Nanjing Red Cross Blood Center
19. Beijing Red Cross Blood Center
Publication Type:Journal Article
Keywords: blood donors; hepatitis B virus; yield; first-time blood donors; repeated blood donors; HBsAg ELISA; HBV DNA
From: Chinese Journal of Blood Transfusion 2023;36(2):172-176
CountryChina
Language:Chinese
Abstract: 【Objective】 To analyze the hepatitis B virus (HBV) infection data of blood donors from 18 domestic blood stations, so as to investigate the HBV infection situation of blood donors. 【Methods】 The positive rate of HBV and its distribution characteristics of regions, the percentage of HBsAg+ ELISA in first-time vs repeated blood donors, and the percentage of HBsAg-/HBV DNA+ blood donors of 18 domestic blood stations during 2017 to 2020 were collected from the Working Platform for Practice Comparison of Blood Centers, and the HBV infection among blood donors were statistically analyzed. 【Results】 From 2017 to 2020, the positive rate of HBV in blood donors among 18 domestic blood stations was 13.48/10 000-144.02/10 000, with the average HBV positive rate in eastern, central and western region at 26.14/10 000, 51.98/10 000 and 41.00/10 000, respectively. The HBsAg+ rate by ELISA among first-time and repeated blood donors was 14.55/10 000-305.39/10 000 vs 1.04/10 000-87.43/10 000 The HBsAg-/HBV DNA+ yield was 1.80/10 000-35.31/10 000. 【Conclusion】 The distribution of HBV infection in blood donors has regional characteristics, and HBV prevalence was low in repeated blood donors. HBsAg ELISA combined with HBV DNA detection can better ensure blood safety.