Study on the distribution of ABO blood group in patients with pancreatic cancer
10.13303/j.cjbt.issn.1004-549x.2023.02.014
- VernacularTitle:胰腺癌患者ABO血型分布相关性研究
- Author:
Xiaoliang YANG
1
;
Xiaoqin ZHOU
2
;
Jing LI
3
;
Xia ZHONG
1
;
Kun WANG
4
;
Xiaoyan TANG
1
;
Xing GU
1
Author Information
1. Department of Blood Transfusion, Jiading Campus, The Third Affiliated Hospital of Naval Military Medical University, Shanghai 201805, China
2. Area B of the First Department of Interventional Radiology, Jiading Campus, The Third Affiliated Hospital of Naval Military Medical University, Shanghai 201805, China
3. One Ward of the Second Department of Extrahepatic Surgery, Jiading Campus, The Third Affiliated Hospital of Naval Military Medical University, Shanghai 201805, China
4. Department of Laboratory Diagnosis, Jiading Campus, The Third Affiliated Hospital of Naval Military Medical University, Shanghai 201805, China
- Publication Type:Journal Article
- Keywords:
digestive tract neoplasms;
pancreatic cancer;
blood group distribution
- From:
Chinese Journal of Blood Transfusion
2023;36(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate whether there is a correlation between the differences in ABO blood group distribution in patients with pancreatic cancer, and to evaluate the relative risk. 【Methods】 Patients with pathological diagnosis or discharge diagnosis of pancreatic cancer who underwent ABO blood group typing in our hospital from January 2017 to October 2021 were selected, and the blood group distribution of patients and the correlation were analyzed. 【Results】 There was a statistically significant difference between the pancreatic cancer group and the control group (P<0.05). The study showed that type A may be a relative risk factor for pancreatic cancer patients (χ2=42.44, P<0.001), and type B may play a protective role (χ2=16.28, P<0.01). Significant differences were found in distribution between different gender groups (χ2=64.35, P<0.05). The test results showed that type A may be a risk factor for pancreatic cancer in men (χ2=35.2, OR=1.7, 95%CI=0.59-1.02, P<0.001), and type O may play a protective role in pancreatic cancer(χ2=18.22, OR=0.6, 95%CI=0.25-0.32, P<0.01); type A may be a relative risk factor for female pancreatic cancer patients (χ2=7.06, OR=1.4, 95%CI=0.59-1.02, P<0.001), while type B may play a protective role (χ2=20.32, OR=0.5, 95%CI=0.32-0.43, P<0.01). In pancreatic cancer group, the risk factors of blood type A were higher than those of non-A group, and the protective effect of type B was significantly higher than that of non-B group. 【Conclusion】 The distribution of blood group and relative risk factors in pancreatic cancer patients suggest that A type is predominant; in the population with A blood group, more attention should be paid to early prevention and early treatment, so as to reduce the risk of disease.
