HPV B19, HAV and HEV infection among voluntary blood donors in Nantong
10.13303/j.cjbt.issn.1004-549x.2023.05.017
- VernacularTitle:南通地区无偿献血者HPV B19、HAV和HEV感染状况研究
- Author:
Kecheng WANG
1
;
Yingzhou DING
1
Author Information
1. Nantong Blood Center, Nantong 226014, China
- Publication Type:Journal Article
- Keywords:
human parvovirus B19;
hepatitis A virus;
hepatitis E virus;
nucleic acid test;
voluntary blood donors
- From:
Chinese Journal of Blood Transfusion
2023;36(5):444-447
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To evaluate the viability of nucleic acid test(NAT) of human parvovirus B19 (HPV B19), hepatitis A virus (HAV) and hepatitis E virus (HEV) along with routine NAT for voluntary blood donors, and to analyze HPV B19, HAV and HEV prevalence in Nantong, so as to provide reference for rational blood screening programs. 【Methods】 HPV B19 DNA, HAV RNA and HEV RNA of blood donors in Nantong from November 2021 to May 2022 were detected using NAT, and serological antibody testing was performed on NAT reactive samples. 【Results】 Three HPV B19 DNA was yielded out of 3 440 blood donors, with a positive rate of 0.09%, among which 2 were negative for HPV B19-IgM and 1 was undetermined due to insufficient sample size. HAV RNA and HEV RNA were not detected in 3 440 blood donors. HPV B19, HAV, and HEV NAT were conducted simultaneously with routine HBV, HCV and HIV screening, prolonging the test reports by 20 minutes. 【Conclusion】 Although the HPV B19 DNA, HAV RNA and HEV RNA prevalence among voluntary blood donors in Nantong is low, the risk of transfusion transmitted infection still exsits and can be reduced by NAT.
