Progress in immune hemolytic anemia caused by drugs
10.13303/j.cjbt.issn.1004-549x.2023.06.022
- VernacularTitle:药物诱导的免疫溶血性贫血研究进展
- Author:
Xinyan LONG
1
;
Leiping WANG
1
;
Yinze ZHANG
2
;
Qingbao MENG
1
Author Information
1. Shenzhen People’s Hospital, Shenzhen 518020, China
2. Shenzhen University General Hospital
- Publication Type:Journal Article
- Keywords:
immune hemolytic anemia;
drug-dependent antibodies;
direct coombs test
- From:
Chinese Journal of Blood Transfusion
2023;36(6):553-556
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced immune hemolytic anemia (DIIHA) is a rare cytopenia caused by damage to RBCs by drug-induced antibodies or non-immune protein adsorption (NIPA). The drugs associated with DIIHA and the mechanistic hypotheses that are thought to be involved have been controversial, with complex serological tests often required by specialized Immune Hematology laboratories for diagnosis. It is necessary to know the clinical manifestation and laboratory diagnosis of DIIHA in order to distinguish the immuno-hematological abnormality caused by drugs from other causes. How to improve the diagnostic ability of DIIHA and establish a scientific and reasonable idea of DIIHA serological examination is urgent to help clinical diagnosis and correct treatment.
