Risk factors of transfusion-related circulating overload in inpatients and their relationship with clinical outcome
10.13303/j.cjbt.issn.1004-549x.2023.06.011
- VernacularTitle:住院患者输血相关循环超负荷的危险因素以及与临床结局的关系分析
- Author:
Yu ZHAO
1
;
Mengmeng HAO
1
;
Xixi LIU
1
;
Yongtong CAO
1
Author Information
1. Blood Transfusion Department, Sino-Japanese Friendship Hospital, Beijing 100029, China
- Publication Type:Journal Article
- Keywords:
transfusion related circulation overload;
heart failure;
pulmonary edema;
chronic kidney disease;
positive liquid balance;
risk factor
- From:
Chinese Journal of Blood Transfusion
2023;36(6):504-507
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the risk factors of transfusion-related circulating overload (TACO) in hospitalized patients and to analyze its impact on clinical outcome. 【Methods】 The clinical data of 295 patients with blood transfusion admitted to our hospital from June 2020 to June 2022 were retrospectively analyzed. The patients were divided into TACO group (n=23) and control group (n=272) according to the incidence of TACO. The risk factors of TACO were analyzed by Logistic regression, and the differences of hospital stay and mortality between the TACO group and the control group were compared. 【Results】 TACO occurred in 23 of 295 patients, accounting for 7.80% of all transfusion reactions. The incidence of TACO in different transfusion components was different. Elder age, history of heart failure, history of chronic kidney disease, large mean blood transfusion volume, positive fluid balance [OR(95%CI)): 2.022 (1.212-3.372), 1.917(1.258-2.922), 1.719 (1.155-2.560), 2.252 (1.256- 4.039), 2.221 (1.358-3.633)] were the main risk factors for TACO (P<0.05). 【Conclusion】 Elder age, history of heart failure, history of chronic kidney disease, large blood transfusion volume and positive fluid balance were risk factors for TACO, and TACO was associated with increased length of stay and mortality during hospitalization.
