Research status of additives related to platelet preservation
10.13303/j.cjbt.issn.1004-549x.2023.07.022
- VernacularTitle:血小板保存相关添加剂研究现状
- Author:
Mengxue LI
1
;
Zhicheng WANG
1
Author Information
1. Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China
- Publication Type:Journal Article
- Keywords:
platelet transfusion;
platelet additive solutions;
platelet storage;
platelet storage lesion
- From:
Chinese Journal of Blood Transfusion
2023;36(7):647-650
- CountryChina
- Language:Chinese
-
Abstract:
Platelets play an important role in hemostasis, inflammation, tumor metastasis, wound healing and defense response, but its routine storage requires a specific temperature and the storage time is generally limited to 5 ~7 d, at the same time, platelet storage damage and bacterial breeding will limit its storage time. In addition, routine transfusion can cause serious adverse reactions such as non-hemolytic fever, allergies, circulatory overload, and transfusion-related acute lung injury. These limit the clinical application of platelet products. However, additives associated with platelet preservation can reduce the likelihood of their occurrence. Therefore, this article reviews the research status of additives related to platelet preservation in recent years, as well as improving platelet storage damage and improving platelet preservation characteristics.
