Research progress of platelet lysates in the field of regenerative medicine and cell therapy
10.13303/j.cjbt.issn.1004-549x.2023.07.021
- VernacularTitle:血小板裂解物在再生医学和细胞治疗领域的研究进展
- Author:
Jiahui ZUO
1
;
Yiming LI
1
;
Shuwei YANG
1
;
Liqin HUANG
1
Author Information
1. Shenzhen Blood Center, Shenzhen 518035, China
- Publication Type:Journal Article
- Keywords:
human platelet lysates (HPL);
cell therapy;
regenerative medicine;
cell culture supplement;
preparation standardization
- From:
Chinese Journal of Blood Transfusion
2023;36(7):642-646
- CountryChina
- Language:Chinese
-
Abstract:
Human platelet lysates(HPL), as a new type of biomaterial, can promote tissue repair, cell proliferation and inflammation control. This paper introduced the development of HPL in the field of regenerative medicine and cell therapy and summarizes their application. The potential of HPL to promote cell proliferation was used as an entry point to show its advantages as a supplement of cell culture medium. Since there is currently no standard procedure for HPL preparation, this paper sorts out the standardization elements such as raw materials source, donor variability and preparation technology, in order to provide reference for the establishment of standards of relevant industry in the future.