Advances in the application of lyophilized platelets and derivative products

VernacularTitle:冻干血小板及衍生制品应用的研究进展
Author: Wenjuan LI ^{1
,

2} ; Shuchao ZHANG ^{2
,

3}
Author Information

1. Blood Transfusion Department, Chengwu County People's Hospital, Chengwu 274200, China
2. Department of Immunology, College of Basic Medicine, Qingdao University
3. Blood Transfusion Department, The Affiliated Hospital of Qingdao University
Publication Type:Journal Article
Keywords: lyophilized platelets; hemorrhage; wound healing; tissue repairing
From: Chinese Journal of Blood Transfusion 2023;36(8):745-750
CountryChina
Language:Chinese
Abstract: Platelets are important components of the blood system. There are many kinds of concentrated platelets and their derivatives, among which platelet-rich plasma (PRP ), growth factors (GFs) and platelet-rich fibrin (PRF) have been widely used in clinical practice. Lyophilized platelets (Lyo-P) or freeze-dried platelets (FDP) are prepared from concentrated platelets by freeze-drying and have the advantages of long storage time at room temperature, light weight, convenient transportation, inactivation of pathogens, etc. Lyo-P contain high concentration of GFs, fibrin, white blood cells and various cytokines. In addition to their hemostatic and coagulative functions, Lyo-P and their products are increasingly used in wound healing, tissue repair, cosmetology, reproductive medicine and other fields.