Centralized blood nucleic acid test data in Tibet: a retrospective analysis
10.13303/j.cjbt.issn.1004-549x.2023.08.017
- VernacularTitle:西藏地区血液集中化检测核酸筛查数据的回顾性分析
- Author:
Xiaojuan LI
1
;
Ningfei YANG
2
;
Rui MAO
3
;
4
;
5
;
Yujiang LI
6
;
7
;
8
Author Information
1. Blood Center of Tibet Autonomous Region, Lhasa 850000, China
2. Hospital Laboratory, Chengdu Office, Tibet Autonomous Region People's Government
3. Xi'an Children's Hospital
4. Ngari Central Blood Station
5. Shigatse Central Blood Station
6. Nyingchi Central Blood Station
7. Shannon Central Blood Station
8. Naqu Central Blood Station
- Publication Type:Journal Article
- Keywords:
centralized detection;
nucleic acid testing;
blood safety;
Tibet region
- From:
Chinese Journal of Blood Transfusion
2023;36(8):724-727
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To retrospectively analyze the serological and nucleic acid testing(NAT) data of voluntary blood donors from six blood banks in Tibet, in order to explore the positive impact of NAT on reducing the risk of infective transfusion in a regional scope. 【Methods】 From 2018 to 2022, 38 718 voluntary blood donors from blood centers of Tibet, Shannan, Shigatse, Naqu, Nyingchi and Ngari were tested for hepatitis B virus surface antigen (HBsAg), hepatitis C virus antibody (anti-HCV), human immunodeficiency virus antigen (HIV) and antibody (Ag/Ab1+2) serological determination by enzyme-linked immunosorbent assay (ELISA). At the same time, Haoyuan and Daan nucleic acid detection systems were used for the combined detection of HBV-DNA, HCV-RNA and HIV-RNA. The results of NAT of reactive ELISA samples were statistically analyzed. 【Results】 A total of 178 ELISA-/NAT+ samples were detected in Tibet over the past five years, including 170 HBV-DNA positive cases, 8 HCV-RNA positive cases, and 0 HIV-RNA positive cases, with the positive rate at 0.460%.The detection rate of 624 ELISA+/NAT+ samples was 1.61%.The age of blood donors with hepatitis B in Shigatse area was slightly higher than that in other areas, and the difference was statistically significant(P<0.05) . 【Conclusion】 The centralized detection of viral nucleic acid in Blood Center of Tibet Autonomous Region can effectively reduce the missed detection of transfusion transmitted diseases and guarantee the blood safety in the region.
