Frequency survey of blood group PP1PK in Chinese Lahu Population

VernacularTitle:中国拉祜族PP1PK血型频率调查
Author: Haixia HU ¹ ; Liangfeng FAN ² ; Chengjiang FANG ¹ ; Dong XIANG ² ; Dan WU ¹
Author Information

1. Puer Blood Center, Puer 665000, China
2. Shanghai Blood Center
Publication Type:Journal Article
From: Chinese Journal of Blood Transfusion 2023;36(9):847-850
CountryChina
Language:Chinese
Abstract: 【Objective】 To investigate the frequency of P1PK and GLOB blood group in Chinese Lahu population and their genetic status, so as to provide data support for the safety of blood transfusion and give advice and transfusion guidance for pregnant women. 【Methods】 Unrelated individuals of Chinese Lahu population were randomly selected for serological identification of P1PK and P blood group and gene sequencing analysis. The frequency of P1PK and GLOB blood group were analyzed. 【Results】 Six cases of anti-PP 1P^k(formerly known as anti-Tj^a) negative blood type were identified as the rare P1-PK-P- blood type (formerly known as Tj^a- blood type or p blood type, hereinafter referred to as p blood group) from 300 Lahu population, with phenotypic frequency of p blood group in P1PK and GLOB blood group system in Lahu population at 2.0%(6/300). 【Conclusion】 The phenotypic frequency of blood group p in Lahu population was significantly higher than that in Europe (5.8 persons per million) and Hong Kong, China (1 person per million),indicating significant ethnic specificity and regional ethnic differences.