The Association of Abnormal Maternal Serum Alpha-fetoprotein with Adverse Pregnancy Outcome.
- Author:
JI Young KIM
;
Cheong Rae ROH
;
Jong Won KIM
;
Soon Ha YANG
;
Chang Soo PARK
;
Doo Seok CHOI
;
Jae Hyun CHUNG
;
Byung Koo YOON
;
Duck Soo BAE
;
Je Ho LEE
- Publication Type:Original Article
- Keywords:
Meternal serum alpha-fetoprotein;
Adverse pregnancy outcome
- MeSH:
Abruptio Placentae;
alpha-Fetoproteins*;
Case-Control Studies;
Female;
Fetal Development;
Follow-Up Studies;
Humans;
Mothers;
Placenta Previa;
Pre-Eclampsia;
Pregnancy;
Pregnancy Outcome*;
Pregnancy*;
Pregnant Women;
Retrospective Studies
- From:Korean Journal of Perinatology
1997;8(1):43-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE:To determine whether elevated or low levels of maternal serum alpha- fetoprotein(AFP) measured at 15-20 weeks of gestation predict increased risk of adverse pregnancy outcome, including preterm birth(before 36 weeks of gestation), fetal growth retardation(FGR), preeclampsia, placental abruption, FDIU, placenta previa and fetal anomaly. METHOD: Data of pregnancy outcomes in singleton pregnancies with elevated or low maternal serum AFP levels measured at 15-20 weeks of gestation were gathered retrospectively. As a part I study, case-control study including 106 women with maternal serum AFP) 2.0 MOM(Multiples of median) and matched control group of 212 women with 0.5 MOM
