Preparation quality control and clinical application observation of pooled platelets with leukocytes reduced
- VernacularTitle:去白细胞混合浓缩血小板制备的质量控制及临床应用效果观察
- Author:
Min GUO
1
;
Jianmin LI
1
;
Jianhui LIU
2
;
Ning YANG
1
;
Jing ZHANG
1
;
Yuqiu LI
1
;
Fei CHENG
1
;
Xuzhi LIU
1
;
Qiang HE
1
;
Miao HE
1
;
Wenjuan YANG
1
Author Information
- Publication Type:Journal Article
- Keywords: pooled platelets leukocytes reduced; apheresis platelets leukocytes reduced; application effect
- From: Chinese Journal of Blood Transfusion 2023;36(11):1025-1028
- CountryChina
- Language:Chinese
- Abstract: 【Objective】 To investigate the preparation quality and clinical application effect of pooled platelets with leukocytes reduced. 【Methods】 The quality and clinical effect of the buffy-coated method prepared pooled platelets leukocytes reduced (experimental group, n=40) and apheresis platelets leukocytes reduced (control group, n=40) were compared. 【Results】 The platelet volume (mL), platelet count (×1011), red blood cell contamination (×108) and residual white blood cell (×106) of the experimental group and control group were 278.90±7.92 vs 276.52±8.01, 2.66±0.09 vs 2.66±0.83, 0.54±0.42 vs 0.83±0.84, 0.29±0.54 vs 0.27±0.51, respectively, with no significant difference. The results of bacterial culture were negative, all met the requirements of relevant national standards. In addition, the CCI (×103, 24 h) and PPR (%) were 15.11±9.86 vs 14.61±12.55 and 54.23±18.70 vs 61.41±19.09 respectively, with no significant difference, indicating a certain degree of therapeutic effect. 【Conclusion】 The quality and clinical therapeutic effect of pooled platelets leukocytes reduced were consistent with that of apheresis platelets leukocytes reduced.
