Application of CT pulmonary angiography in acute pulmonary embolism and right heart function
10.3969/j.issn.1006-9771.2023.12.007
- VernacularTitle:CT肺动脉造影对康复患者急性肺栓塞及右心功能的评价
- Author:
Hongxia ZHANG
1
;
Xinying CONG
1
;
Tian ZHANG
1
;
Ye WU
1
;
Qing LI
1
;
Xuejing LI
1
;
Yifan CHEN
1
;
Xiuting WANG
1
;
Weiyong YU
1
;
Zhenbo CHEN
1
Author Information
1. Department of Imaging, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
- Publication Type:Journal Article
- Keywords:
CT pulmonary angiography;
acute pulmonary embolism;
right heart function
- From:
Chinese Journal of Rehabilitation Theory and Practice
2023;29(12):1429-1438
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the application value of CT pulmonary angiography (CTPA) in assessing the severity of acute pulmonary embolism (APE) and right heart function in rehabilitation patients. MethodsFrom January, 2013 to January, 2020, 133 inpatients (94 positive and 39 negative) who underwent CTPA examination in Beijing Bo'ai Hospital were involved. Positive patients were further divided into mild, moderate and severe groups based on the pulmonary artery obstruction index (PAOI). The clinical parameters and right heart function indicators were compared. Spearman correlation analysis was used to analyze the correlation between PAOI, and clinical parameters and right heart function indicators, and Logistic regression analysis was used to predict the risk factors of APE. ResultsThere was significant difference in lower extremity venous thrombosis, D-dimer, oxygen partial pressure, PAOI and left process of interventricular septum among four groups (H ≥ 12.350, P < 0.01). PAOI was moderately positively correlated with D-dimer (r = 0.443, P < 0.001) and left process of interventricular septum (r = 0.520, P < 0.001), and was weakly positively correlated with lower extremity venous thrombosis (r = 0.399, P < 0.001), left pulmonary artery diameter (r = 0.213, P = 0.014) and inferior vena cava regurgitation (r = 0.229, P = 0.008). Lower extremity venous thrombosis (OR = 7.708, P < 0.001) and left process of interventricular septum (OR = 3.641, P = 0.008) were independent risk factors for the onset of APE. The combination of the two indicators was effective for diagnosis of APE, and AUC was 0.795 (95% CI 0.715 to 0.874). ConclusionCTPA may be applied to evaluate the severity of APE and right heart function in rehabilitation patients.