Serological and molecular investigation of B (A) blood group and its transfusion strategy: A case report
10.13303/j.cjbt.issn.1004-549x.2021.02.026
- VernacularTitle:B(A)血型血清学及分子生物学家系调查及输血策略分析
- Author:
Lihui FU
1
;
Chunya MA
1
;
Xiaolin SUN
1
;
Yueqing WU
2
;
Yang YU
1
;
Deqing WANG
1
Author Information
1. Department of Blood Transfusion, First Medical Center, Chinese People′s Liberation Army General Hospital, Beijing 100853, China
2. Department of Blood Transfusion, Hainan Hospital, Chinese People′s Liberation Army General Hospital
- Publication Type:Journal Article
- Keywords:
B(A) blood group;
serological typing;
genetic typing;
family study
- From:
Chinese Journal of Blood Transfusion
2021;34(2):188-190
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To study the serological and genetic characteristics of a case of B(A) blood group. 【Methods】 Serological and genetic ABO blood group typing were used to analyze the ABO subtype and family inheritance of the probands and her 8 family members. The B(A) blood type sample was used as the blood recipient, and the B-type and O-type donors were selected for cross-matching using microcolumn gel anti-human globulin method to evaluate the blood transfusion strategy. 【Results】 5 out of 9 family blood samples were B(A) phenotype, carrying B(A)04 allele. Among them, 1 was B(A)04/O1 type, and 4 were B(A)04/B type. The primary blood matching of B(A) blood type samples with type B and O recipients were all negative. 【Conclusion】 A total of 5 cases of B(A)04 blood type were found in this family investigation, and there were differences in serological manifestations. Washed RBCs with B and O type can be used for B(A) blood type transfusion, and type B suspended RBCs can be considered in case of emergency.
