Storage duration of suspendedred blood cells affects the efficacy of blood transfusion in patients with aplastic anemia
10.13303/j.cjbt.issn.1004-549x.2021.02.013
- VernacularTitle:悬浮红细胞储存时间影响再生障碍性贫血患者悬浮红细胞输注疗效
- Author:
Huanhuan ZHOU
1
;
Xianping ZHOU
1
Author Information
1. Department of Transfusion, the People′s Hospital of Bozhou, Bozhou 236800, China
- Publication Type:Journal Article
- Keywords:
aplastic anemia;
suspended RBCs;
storage duration of RBCs
- From:
Chinese Journal of Blood Transfusion
2021;34(2):146-149
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To study the impact of the storage duration of suspendedred blood cells(RBCs)on blood transfusion for patients with aplastic anemia. 【Methods】 76 occasions of blood transfusions for 36 patients with aplastic anemia, admitted to our hospital between 2017~2019, were observed. The effects of patient and donordemographics as well as storage duration on the efficacy of RBCs transfusion were analyzed using linear regression. 【Results】 Multivariate linear regression analysis revealed that the efficacy of RBCs transfusion was negatively correlated with the patient′s weight (P<0.01) and the storage duration of suspended RBCs (P<0.05). Female recipients and male donors incurred better efficacy in RBCs transfusion. Further analysis revealed that, compared to units stored ≤7 days, transfusion of perunit ofsuspended RBCs stored 8 to 14 dor≥15 dresulted in hemoglobin decreasing as -0.619 (95% CI: -1.943-0.704; P>0.05) and -1.904 (95% CI: -3.750~-0.057; P<0.05) g/L, respectively, presenting a gradually decreasing trend. 【Conclusion】 Longer storage of RBCs has an impact on the efficacy of blood transfusion in patients with aplastic anemia.
