Influencing factors of perioperative red blood cell transfusion in patients underwent lung transplantation
10.13303/j.cjbt.issn.1004-549x.2021.02.010
- VernacularTitle:肺移植患者围术期红细胞输注量的影响因素分析
- Author:
Wenjing WANG
1
;
Qi WANG
1
;
Ru ZHAO
1
;
Lida CHEN
1
;
Lulu WANG
1
;
Weijie GUO
1
;
Xixi LIU
1
;
Fan ZHANG
1
;
Xirong HE
1
;
Hongkai LU
1
Author Information
1. Department of Blood Transfusion, China-Japan Hospital, Beijing 100029, China
- Publication Type:Journal Article
- Keywords:
perioperative blood transfusion;
red blood cell transfusion;
lung transplantation;
massive blood transfusion;
intraoperative blood loss;
the operation duration;
ECMO;
patients blood management
- From:
Chinese Journal of Blood Transfusion
2021;34(2):135-139
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the influencing factors of perioperative red blood cell transfusion in patients underwent lung transplantation, so as to provide reference for perioperative blood management (PBM) of lung transplantation patients. 【Methods】 The clinical data of 173 lung transplant patients completed in China-Japan Friendship Hospital from March 2017 to June 2019 were retrospectively analyzed. The patients were divided into two groups according to perioperative red blood cell transfusion volume: large blood transfusion group (transfusion red blood cell volume ≥6 U, n=66) and non-large blood transfusion group (red blood cell transfusion volume <6 U, n=107). The basic information, preoperative laboratory test results, and surgical status of the two groups were statistically analyzed.The clinical data of the two groups were analyzed by univariate analysis. The factors of P<0.15 were included in the binary logistic regression analysis, and the independent influencing factors of perioperative massive blood transfusion in patients with lung transplantation were found. 【Results】 Univariate analysis of clinical data of the two groups of patients (large blood transfusion group vs. non-large blood transfusion group) showed that the differences of smoking history ratio [44(66.7%) vs 87(81.3%)], BMI(20.8±4.5 vs 22.5±4.0)(P<0.05), preoperative Hb [124(111, 138.8) vs 138(126, 149)], preoperative Hct [37.9(34.8, 42.5) vs 41.3(37.9, 44.6)], surgery duration(327.9±107.7 vs 238.4±77.0), intraoperative blood loss(1 108.6±1342.0 vs 341.8±270.8) and single lung transplantation [28(42.4%) vs 84(78.5%)] (P<0.01) were statistically significant. Logistic regression analysis showed that intraoperative blood loss (OR=1.001, P<0.05), surgery duration (OR=1.006, P<0.05), preoperative Hb (OR=0.973, P<0.01), lung transplantation type(single or double lung transplantation)( OR=0.247, P<0.05) and extracorporeal membrane oxygenation (ECMO) (OR=0.187, P<0.01) were independent factors influencing red blood cell transfusion during lung transplantation. 【Conclusion】 Intraoperative blood loss and surgery duration are risk factors for massive blood transfusion during the perioperative period. And the use of ECMO, preoperative Hb, single lung transplantation (compared to double lung transplantation) are protective factors for perioperative massive blood transfusion.
