Quality analysis of platelet concentrates prepared with optimized blood collection bags
10.13303/j.cjbt.issn.1004-549x.2021.05.024
- VernacularTitle:调整优化采血联袋后制备浓缩血小板的质量分析
- Author:
Daling XIAO
1
;
Kun YANG
1
;
Jiashou WEI
1
;
Xinbao HUANG
1
;
Guokui LIN
1
;
Jueyu TAO
1
;
Yonghong HE
1
Author Information
1. Guigang Central Blood Station, Guigang 537100, China
- Publication Type:Journal Article
- Keywords:
blood collection bag;
platelet quality;
blood transfusion safety;
adjustment and optimization
- From:
Chinese Journal of Blood Transfusion
2021;34(5):535-537
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To evaluate the quality of platelet concentrates prepared by two different blood collection bags, so as to provide references for the development of high-quality platelet preparation. 【Methods】 Platelet concentrates were prepared using buffy coating from the whole blood collected by conventional and optimized single-use blood collection bags with leukoreduction filter, respectively. The volume of whole blood collected was 400 mL, and 60 bags in total. They were divided into group A (conventional collection bags, n=30), and the size of buffy coating pouch was 15 cm×12 cm; group B (optimized collection bags, n=30), and the size of buffy coating pouch was 11 cm×9 cm. 【Results】 There were significant differences between group A and group B in the amount of red blood cells contamination, platelet content, and platelet yielding rate (P<0.05), which were (2.62±0.57)×109/mL vs (1.37±0.35)×109/mL, (4.41±0.31)×1010/mL vs (6.21±0.63)×1010/mL, and (55.03±0.06)% vs (79.23±0.09)%, respectively. 【Conclusion】 The buffy coating pouch with the size of 11 cm×9 cm can produce better platelet concentrates, thus improves the safety and efficacy of clinical blood transfusion.
