Unqualified rate of anti-HIV detection in the laboratories from blood banks in Beijing-Tianjin-Hebei region
10.13303/j.cjbt.issn.1004-549x.2021.04.012
- VernacularTitle:京津冀血站实验室抗-HIV检测不合格情况分析
- Author:
Wei ZHEN
1
;
Hongwei GE
1
;
Rui WANG
1
;
Tong PAN
2
;
Wei HAN
3
;
Peng WANG
4
;
Li YANG
5
;
Shaoqiu SUN
6
;
Xiao CAO
6
;
Liye CUI
7
;
Chao WEI
8
;
Guijun YU
8
;
Yunpeng XU
9
;
Jinjuan FANG
10
;
Caixia LIU
11
;
Xuegang WANG
12
;
Zhijun ZHEN
13
;
Xiaojie LIU
14
;
Wengong DU
15
;
Lunan WANG
16
;
Jiang LIU
1
;
Hongjie WANG
1
Author Information
1. Beijing Red Cross Blood Center, Beijing 100088, China
2. Tianjing Blood Center
3. Hebei Blood Center
4. Tongzhou Blood Bank
5. Tanggu Blood Bank
6. Tangshan Blood Bank
7. Baoding Blood Bank
8. Cangzhou Blood Bank
9. Zhangjiakou Blood Bank
10. Hengshui Blood Bank
11. Chengde Blood Bank
12. Handan Blood Bank
13. Xingtai Blood Bank
14. Qinhuangdao Blood Bank
15. Langfang Blood Bank
16. National Center for Clinical Laboratories
- Publication Type:Journal Article
- Keywords:
blood screening laboratory;
the unqualified rate of anti-HIV detection;
unqualified;
blood donors;
blood bank;
Beijing-Tianjin-Hebei region
- From:
Chinese Journal of Blood Transfusion
2021;34(4):371-376
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the unqualified rate of anti-HIV detection of blood screening laboratories in Beijing-Tianjin-Hebei region, and explore the differences in anti-HIV detection ability and influencing factors in each laboratory. 【Methods】 Through filling questionnaires via e-mail, the anti-HIV ELISA unqualified rate and confirmed (WB) positive results (data) from January to December 2018 from 15 blood screening laboratories in Beijing-Tianjin-Hebei region were collected. Our laboratory was responsible for data collection and confirmation, and statistics software SPSS22.0 was used for analysis. 【Results】 1) There was a statistically significant difference among the unqualified rate of anti-HIV ELISA(6.77‱~35.71‱) and confirmed positive rate(0.60‱~3.56‱) in 15 blood screening laboratories in Beijing-Tianjin-Hebei region (P<0.05); 2) There were significant differencse among the ELISA unqualified rate and the confirmed positive rate of 8 reagents for anti-HIV detection(P<0.01), and the sensitivity of the 4th generation detection reagent and the imported reagent was higher than that of the 3rd generation reagent and the domestic reagent. The anti-HIV ELISA unqualified rate of R5 was the highest (19.08‱). 3)There were significant differences in the anti-HIV ELISA unqualified rate of R1, R2, R3, R5 and R7 reagents among different blood station laboratories(P<0.05), and there were no significant differences in the anti-HIV ELISA unqualified rate of R4, R6 and R8 reagents among different blood station laboratories(P>0.05). 4)The unqualified rate of anti-HIV ELISA of laboratories using different regents showed significant differences(P<0.05), except H, J, M. The unqualified rate of imported reagent was significantly higher than that of domestic reagents of laboratories using imported and domestic reagents combinations(P<0.05), except O. 62.5% (5/8) laboratories using domestic 3rd and 4th generation reagent combination showed significant differences in the unqualified rates among different reagents(P<0.05); 5) The positive rate of single-reagent(62.02%~95.45%)in 15 blood screening laboratories showed significant difference(P<0.001), and A was the lowest (62.02%). 【Conclusion】 The anti-HIV detection ability among 15 blood screening laboratories in Beijing-Tianjin-Hebei region is quite different. The application of different reagents is the main factor for the difference, and other factors such as personnel, instruments and test strategies also has a great impact on the detection of anti-HIV. It is still necessary to promote the process of homogenization of blood testing quality among blood screening laboratories in Beijing-Tianjin-Hebei region.
