Hepatitis B screening of voluntary blood donors and characteristics of HBV positive population, Chongqing
10.13303/j.cjbt.issn.1004-549x.2021.07.018
- VernacularTitle:重庆地区无偿献血者HBV筛查结果及其阳性人群特征分析
- Author:
Xiaoqin XIE
1
;
Fang WANG
1
Author Information
1. Chongqing Blood Center, Chongqing 400015, China
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
voluntary blood donors;
population distribution;
Chongqing
- From:
Chinese Journal of Blood Transfusion
2021;34(7):743-746
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the characteristics and prevalence of HBV infection among voluntary blood donors in Chongqing and analyze its epidemiological characteristics, so as to provide reference for effective selection of low-risk blood donors. 【Methods】 The test results of hepatitis B surface antigen (HBsAg) and viral nucleic acid (HBV DNA) of 314 442 voluntary blood donors from October 2017 to October 2020 in Chongqing Blood Center were retrospectively analyzed. The relationship between the total positive rate of HBV, HBsAg+ /HBV DNA-, HBsAg-/HBV DNA+, HBsAg+ /HBV DNA+ and gender, marriage, age, education background, occupation, firs-time blood donation and repeated blood donation was analyzed. 【Results】 Among the 314 442 voluntary blood donors, the total positive rate of HBV, HBsAg+ /HBV DNA-, HBsAg-/HBV DNA+ and HBsAg+ /HBV DNA+ was 0.88% (2 764/314 442), 0.28% (893/314 442), 0.18% (567/314 442) and 0.41% (1 304/314 442), respectively. The total positive rate of HBV, HBsAg-/HBV DNA+ and HBsAg+ /HBV DNA+ was different in gender, marriage, age, education background, occupation and firs-time/repeated blood donation. The positive rate of men was higher than that of women, and that of married higher than that of unmarried, and decreased as the education level elevated.The positive rate of farmers and workers was the highest and that of medical staff was the lowest, followed by students, military personnel, civil servants, and teachers. The positive rate of first-time blood donors was higher than that of repeated blood donors. The differences were statistically significant (P<0.05); The positive rate of HBV, HBsAg-/HBV DNA+ and HBsAg+ /HBV DNA+ within 18~50 years old all increased gradually with age. the positive rate of HBsAg+ / HBV DNA+ was highest within 41~50 years old, and that of HBsAg-/HBV DNA+ was highest within 51~60 years old, with statistical significance (P<0.05). The positive rate of HBsAg+ /HBV DNA- was statistically significant between first-time and repeated blood donation (P<0.05), and there is no significant difference between gender, marriage, age, educational background, and occupation(P>0.05). 【Conclusion】 The prevalence of HBV among voluntary blood donors in Chongqing is relatively high and is related to gender, marriage, age, education background, occupation, and first-time/repeated blood donation. It is necessary to strengthen effective consultation before blood donation, formulate guidelines for blood donation recruitment, select voluntary blood donors from low-risk groups to improve blood safety.
