Autologous platelet-rich plasma(PRP) for treatment of knee arthritis: A comparative study between PRP prepared by manual and automatic plateletapheresis
10.13303/j.cjbt.issn.1004-549x.2021.07.006
- VernacularTitle:手工与全自动法制备富血小板血浆的质量及治疗膝关节疾病的疗效分析
- Author:
Renxue XIANG
1
;
Jianjun WU
1
;
Jiajia WANG
2
;
Jian CAI
2
;
Ronghui SHI
1
;
Shuming ZHAO
1
Author Information
1. Department of Blood Transfusion, GuiQian International General Hospital, Guiyang 550018, China
2. Orthopedics, GuiQian International General Hospital, Guiyang 550018, China
- Publication Type:Journal Article
- Keywords:
autologous platelet-rich plasma;
knee arthritis;
platelet count
- From:
Chinese Journal of Blood Transfusion
2021;34(7):695-698
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the quality of autologous platelet-rich plasma prepared by manual and automatic method and to study the clinical injection therapeutic effects in patient with knee arthritis. 【Methods】 28 patients with knee arthritis in Orthopedics Department of our hospital were enrolled. PRP was prepared manually in 12 patients and automatically in 16. The whole blood of 50~70 mL was drawn from 12 patients and prepared into PRP of 10 mL manually by centrifugation. The 20~30 mL PRP was collected by automatic apheresis. Plt, RBC, WBC and other related indexes of PRP were detected after collection. Among the 28 patients, 12 in the manual group received injection twice, while 16 in the automatic group 4 episodes, with an interval of 15~20 days. The treatment effect was evaluated after the last treatment. 【Results】 The PRP prepared by two methods can both reach the required quality standard of platelet counts..The patient′s pain symptoms relieved significantly after injection treatment and the effect was remarkable. There was no significant difference in clinical efficacy between the two groups. 【Conclusion】 The PRP prepared by manual and automatic methods can be used for injection treatment for patient with knee arthritis. The clinical therapeutic effects were good and worth promotion and application.
