Clinical analysis of COVID-19 blood recipients: 81 patients
10.13303/j.cjbt.issn.1004-549x.2021.08.027
- VernacularTitle:新型冠状病毒肺炎输血患者的临床分析81例
- Author:
Bin ZHANG
1
;
Ming GAO
1
;
Hu ZHOU
1
;
Shaojing YU
1
;
Linfeng DENG
1
;
Fang TANG
1
;
Jin XIONG
1
;
Juan WANG
1
;
Qing WEI
1
Author Information
1. Department of Transfusion, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:Journal Article
- Keywords:
COVID-19;
clinical blood transfusion;
retrospective analysis
- From:
Chinese Journal of Blood Transfusion
2021;34(8):904-907
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To retrospectively analyze the transfusion records of COVID-19 patients from Feb to Mar 2020 in the Optical Valley Branch of Tongji Hospital in Wuhan, and summarize the clinical features and blood use of those patients. 【Methods】 1) The utilization of blood components in 81 blood recipients were collected and retrospectively analyzed; 2) Propensity score matching (PSM, by the clinical classification of COVID-19) was used to match the transfused and non-transfused patients according to the ratio of 1∶2, and the clinical features of the two groups were compared. 【Results】 The total transfusion rate in our hospital was 5.5%(81/1 463), among which 88.9%(72/81)transfused red blood cell (RBC). Ten patients received RBC transfusion > 20 U, consumed 48.3%(330/680)RBC, 57.5%(53 500/93 100)plasma, 36.2%(42/116)platelets, and 62.3%(114.25/183.25)cryoprecipitates due to ECMO or gastrointestinal bleeding. Compared to non-transfused patients, transfused patients showed worse lab-indexes related to inflammation, infection, and coagulation at admission, higher incidences of acute liver, kidney and cardiac injury, admission to the ICU and mortality(P<0.01). 【Conclusion】 The related functional indexes and prognosis of transfused COVID-19 patients were significantly worse than non-transfused ones. RBC transfusions were dominant, and massive blood transfusions were seldom.
