Performance evaluation of HBsAg screening before blood donation in Dalian
10.13303/j.cjbt.issn.1004-549x.2021.08.021
- VernacularTitle:大连地区献血前HBsAg筛查效果的分析与评价
- Author:
Huihui GAO
1
;
Xuelian DENG
1
;
Xinmei WANG
1
;
Peng SUN
1
;
Xiaochun LIU
1
;
Xiaohan GUO
1
Author Information
1. Dalian Blood Center, Dalian 116001, China
- Publication Type:Journal Article
- Keywords:
HBsAg rapid testing;
HBsAg quantification;
blood donor screening;
performance evaluation
- From:
Chinese Journal of Blood Transfusion
2021;34(8):882-885
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To improve the efficiency and screening strategy by evaluating the performance of HBsAg screening before blood donation in Dalian. 【Methods】 The confirmed HBsAg positive samples were detected qualitatively and quantitatively, and retested with HBsAg rapid testing kit pre-donational used parallelly. Efficiency of HBsAg screening before donation was calculated, and compared between first-time and repeated donors. 【Results】 The pre-donation HBsAg screening was conducted for 199 553 cases, including 95 321 first-time donors (63.2%) and 55 396 repeated donors(36.8%).1 015 donors (first-time/repeated: 999/16) were reactive in HBsAg rapid testing. 113 samples (first-time/repeated: 108/5), initially negative in HBsAg rapid testing, were confirmed HBsAg positive by laboratory testing. The efficiency of pre-donation HBsAg screening for first-time donors(10.9‰) was significantly higher than that of repeated donors(0.3‰)(P<0.05). The positive rate of retesting was 41.1% (39/95), among which 70% were classified as median or strong positive.Significant difference was observed among HBsAg values(IU/mL) [median(range)] of negative, weak positive, median positive and strong positive samples (P<0.05) which were 0.41 (<0.05-11.35), 6.71 (2.49-23.15), 36.48 (7.01->130) and 92.44 (18.7->130), respectively. 【Conclusion】 The HBsAg rapid testing kit used in Dalian Blood Center could meet requirements for blood donor screening before donation, while good efficiency of HBsAg pre-donation screening could be achieved only in first-time blood donors.
