Approaches against the interference of autoantibodies with pre-transfusion compatibility testing
10.13303/j.cjbt.issn.1004-549x.2021.08.001
- VernacularTitle:自身抗体干扰输血相容性检测处理对策
- Author:
Fengxia LIU
1
;
Rong HUANG
1
;
Yongjun WANG
2
;
Ming ZHOU
3
;
Rong GUI
1
;
Yubin XIE
4
;
Jiongcai LAN
5
;
Wei SHEN
6
Author Information
1. The Third Xiangya Hospital of Central South University, Changsha 410013, China
2. The Second Xiangya Hospital of Central South University
3. Hunan Provincial People′s Hospital
4. Changsha Blood Center
5. Nanfang Hospital, Southern Medical University
6. Shanghai Blood Center
- Publication Type:Journal Article
- Keywords:
autoantibodies;
autoimmune hemolytic anemia(AIHA);
blood group identification;
antibody screening;
antibody identification;
cross matching
- From:
Chinese Journal of Blood Transfusion
2021;34(8):803-808
- CountryChina
- Language:Chinese
-
Abstract:
Pre-transfusion compatibility testing is complicated in autoimmune hemolytic anemia (AIHA) patients due to the presence of autoantibodies. Delays in blood transfusion or even life-threatening would occur if blood type, isoantibodies/ autoantibodies of these patients could not be correctly identified to choose the appropriate blood components. Knowing the detection and treatment countermeasures against blood transfusion compatibility in AIHA patients is of great significance to ensure the timeliness and safety of blood transfusion. Based on the research progress at home and abroad, this article summarizes the serological characteristics, autoantibody types, blood group identification methods, antibody screening and antibody identification methods, and blood transfusion strategies about AIHA patients, in order to eliminate the interference of autoantibodies and provide transfusion guidance for the staff of Blood Transfusion Department.
