Investigation of preoperative anemia and perioperative blood transfusion in patients with duodenal papillarycarcinoma in a tertiary hospital
10.13303/j.cjbt.issn.1004-549x.2021.09.018
- VernacularTitle:十二指肠乳头癌患者术前贫血与围术期输血情况分析
- Author:
Yingwei SONG
1
;
Lijuan SONG
2
;
Junting LIU
1
;
Chengrong BIAN
3
;
Hongfei ZHANG
1
;
Ting ZHANG
1
;
Deqing WANG
1
Author Information
1. Department of Transfusion Medicine, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
2. Brain Science Research Center, College of Integration Science, Yanbian University
3. Center of Clinical Laboratory, the Fifth Medical Center of Chinese PLA General Hospital
- Publication Type:Journal Article
- Keywords:
preoperative anemia;
blood transfusion;
duodenal papillary carcinoma;
Whipple surgery
- From:
Chinese Journal of Blood Transfusion
2021;34(9):1006-1009
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the preoperative anemia and perioperative blood transfusion in patients with duodenal papillary carcinoma who underwent Whipple surgery. 【Methods】 The clinical data of 1 959 cases with duodenal papillary carcinoma, subjected to Whipple surgery, were retrospectively analyzed. 【Results】 The rate of anemia in preoperative patients with duodenal papillary carcinoma was 54.87%(1 075/1 959). The incidence rate of anemia in the three age groups from low to high was 44.92% (≤50 years old, 190/423), 52.82% (51~64 years old, 506/958), and 65.57% (≥65 years old, 379/578) (P<0.05), and the highest rate of anemia occurred in patients aged above 65. There was a significant statistical difference among patients with different body mass index (BMI)(P<0.05). Patients with moderate or severe anemia received more red blood cells than patients with mild anemia during the perioperative period (P<0.05). The average hospitalization time of the blood transfusion patients was 27.25 days, and that of non-transfusion patients was 22.22 days (P<0.05). The amount of blood loss and hospitalization time of patients underwent laparoscopic and robotic surgery were significantly lower than those underwent open surgery patients (P <0.05). There were only 24.09%(186/772) treated with drugs for anemia intervention and the majority of patients (75.91%, 586/772) were treated with blood transfusions to interfere with anemia during hospitalization. 【Conclusion】 There are significant differences in the incidence rate of preoperative anemia among patients with duodenal papillary carcinoma who undergone Whipple surgery. Low BMI, abnormal WBC, and perioperative blood transfusion are high-risk factors for prolonged hospital stay, whereas anemia is not associated with prolonged hospital stay.
