The role of thromboelastography in diagnosis and treatment of PICC related venous thrombosis in tumor patients
10.13303/j.cjbt.issn.1004-549x.2021.09.015
- VernacularTitle:血栓弹力图在肿瘤患者PICC相关性静脉血栓诊疗中的作用
- Author:
Xiaoyan GU
1
;
Haihui YE
1
;
Tingting HU
1
;
Haiying XU
1
Author Information
1. Affiliated Hospital of Hubei University of Arts and Science, Xiangyang Central Hospital, Xiangyang 441021, China
- Publication Type:Journal Article
- Keywords:
tumor patients;
PICC;
venous thrombosis;
thromboelastography
- From:
Chinese Journal of Blood Transfusion
2021;34(9):997-999
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the role of thromboelastography (TEG) in the diagnosis and treatment of PICC related venous thrombosis in tumor patients, and provide basis for predicting PIC related venous thrombosis. 【Methods】 148 tumor patients who underwent PICC catheterization in our hospital from January to July 2019 were enrolled. The patients were subjected to TEG examination and ultrasound examination of limb blood vessels on catheterization side regularly one day before catheterization and 4 successive weeks after catheterization(once a week), respectively. The patients with venous thrombosis were subjected to TEG examination and vascular ultrasound regularly for 3 successive weeks(once a week) after anticoagulant therapy. The relationship between the occurrence and time of venous thrombosis and the changes of TEG parameters was analyzed. 【Results】 The pre-/post-catheterization TEG parameter of 81 patients without venous thrombosis indicated that coagulation state was normal (R value F=0.198, K value F=0.047, α value F=0.442, MAvalue F=0.079, CIvalue F=0.026, P>0.05). The TEG parameter of 67 patients, who developed asymptomatic venous thrombosis 1 to 3 weeks after catheterization(38 cases in 1 week, 16 in 2 weeks and 13 in 3 weeks), indicated the blood was hypercoagulable and the TEG parameter was statistically different from the pre-catheterization value(P<0.01). But after anticoagulant treatment, the coagulation state gradually returned to normal as the TEG parameter reached pre-catheterization value for 3 successive weeks (P>0.05). 【Conclusion】 TEG can reflect the status of PICC related venous thrombosis in tumor patients.Strengthening TEG monitor in tumor patients 1 to 3 weeks after PICC catheterization is conducive to early detection, diagnosis and treatment for PICCrelated thrombosis, thus reducing the harm of venous thrombosis to patients.
